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Cilofexor

CAT: 0013-GTR19167609-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167609-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cilofexor is a potent and selective farnesoid X receptor (FXR) agonist. It functions by binding to and activating FXR, thereby inhibiting the interaction with synthetic peptide ligands. This small molecule is utilized in research on metabolic and liver diseases, including in vitro assays and in vivo models of cholestasis and NASH.
CAS Number
1418274-28-8
Product Name Alternative
Antifibrotic, anti-inflammatory, Autophagy, Cilofexor, GS9674, GS-9674, GS 9674, FXR, inhibit, Inhibitor, NR1H4, nonsteroidal, oral, NASH, safety, PSC
Field of Research
Cell Biology, Metabolism Research
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.82 mM) ; DMSO:125 mg/mL (213 mM)
Smiles
OC (=O) c1ccnc (c1) N1CC (O) (C1) c1ccc (OCc2c (onc2-c2c (Cl) cccc2Cl) C2CC2) cc1Cl
Molecular Formula
C28H22Cl3N3O5
Molecular Weight
586.85
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

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BA3598-1Cilofexor
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A13143-25Cilofexor 25mg
HY-109083ACilofexor (tromethamine)
A13143-500Cilofexor 500mg
A13143-100Cilofexor 100mg
A13143-10Cilofexor 10mg

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