Products for Research Use Only

Brazilin

CAT: 0013-GTR19167571-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167571-02Size:5 mg
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Description
Brazilin is a bioactive small molecule with demonstrated anti-hepatotoxic, antiplatelet, and anti-inflammatory properties. It exhibits cancer-preventive potential by inducing T24 cell death via c-Fos and shows efficacy in cellular models of mastitis and vascular inflammation by inhibiting oxidative stress and NF-κB. This compound is a valuable research tool for studying oncology, immunology, and cardiovascular diseases in vitro.
CAS Number
474-07-7
Product Name Alternative
Superbresiline, Apoptosis, Autophagy, Braziletto, Brazilin, Brasilin, inhibit, Natural Red 24, Inhibitor
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.99 mM) ; DMSO:52 mg/mL (181.64 mM)
Smiles
Oc1ccc2[C@H]3c4cc (O) c (O) cc4C[C@@]3 (O) COc2c1
Molecular Formula
C16H14O5
Molecular Weight
286.28
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Brazilin

Brazilin is a tertiary alcohol, a member of catechols and an organic heterotetracyclic compound. It has a role as an antioxidant, a biological pigment, an antibacterial agent, an antineoplastic agent, a hepatoprotective agent, an anti-inflammatory agent, an apoptosis inducer, a NF-kappaB inhibitor, a plant metabolite and a histological dye.

CAS Number474-07-7
PubChem CID73384
IUPAC Name(6aS,11bR)-7,11b-dihydro-6H-indeno[2,1-c]chromene-3,6a,9,10-tetrol
Molecular FormulaC16H14O5
Molecular Weight286.28
XLogP1.5
Topological Polar Surface Area90.2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Heavy Atom Count21
Formal Charge0
Complexity415
SMILES
C1C2=CC(=C(C=C2[C@H]3[C@@]1(COC4=C3C=CC(=C4)O)O)O)O
InChI
InChI=1S/C16H14O5/c17-9-1-2-10-14(4-9)21-7-16(20)6-8-3-12(18)13(19)5-11(8)15(10)16/h1-5,15,17-20H,6-7H2/t15-,16+/m0/s1
InChIKey
UWHUTZOCTZJUKC-JKSUJKDBSA-N
Chemical Structure
2D Structure
2D structure of Brazilin
CAS: 474-07-7
CID: 73384
Formula: C16H14O5
MW: 286.28
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight286.28
XLogP31.5
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass286.08412354
Monoisotopic Mass286.08412354
Topological Polar Surface Area90.2 Ų
Heavy Atom Count21
Formal Charge0
Complexity415
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes