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Norwogonin

CAT: 0013-GTR19167208-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19167208-02Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Norwogonin (5,7,8-Trihydroxyflavone) is a bioactive flavonoid isolated from Scutellaria baicalensis Georgi. It exhibits antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml) in vitro, making it a candidate for research in virology and antiviral drug discovery.
CAS Number
4443-09-8
Product Name Alternative
Enterovirus, Enterovirus 71 (EV71), EV71, HRV, HRVs, HEV, HEVs, inhibit, infection, Inhibitor, Norwogonin, 5,7,8-Trihydroxyflavone, baicalensis, antiviral, cytotoxicity, Scutellaria, Rhinovirus, Virus Protease, VirusProtease
Field of Research
Infectious Disease & Virology
Purity
98.17% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.4 mM) ; DMSO:20 mg/mL (74.01 mM)
Smiles
Oc1cc (O) c2c (oc (cc2=O) -c2ccccc2) c1O
Molecular Formula
C15H10O5
Molecular Weight
270.24
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Norwogonin

Norwogonin is a trihydroxyflavone with the hydroxy groups at positions C-5, -7 and -8. It has a role as an antioxidant and a metabolite.

CAS Number4443-09-8
PubChem CID5281674
IUPAC Name5,7,8-trihydroxy-2-phenylchromen-4-one
Molecular FormulaC15H10O5
Molecular Weight270.24
XLogP2.7
Topological Polar Surface Area87
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Heavy Atom Count20
Formal Charge0
Complexity412
SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)O
InChI
InChI=1S/C15H10O5/c16-9-6-11(18)14(19)15-13(9)10(17)7-12(20-15)8-4-2-1-3-5-8/h1-7,16,18-19H
InChIKey
ZFKKRRMUPBBYRS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Norwogonin
CAS: 4443-09-8
CID: 5281674
Formula: C15H10O5
MW: 270.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight270.24
XLogP32.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass270.05282342
Monoisotopic Mass270.05282342
Topological Polar Surface Area87 Ų
Heavy Atom Count20
Formal Charge0
Complexity412
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-N2562-01Norwogonin
T126265-01Norwogonin-8-O-glucuronide
380961Norwogonin 5,7,8-trimethyl ether

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