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E3 ligase Ligand 23

CAT: 0013-GTR19166752-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166752-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ligand 23 is a cereblon E3 ligase-binding molecule that induces the ubiquitin-proteasomal degradation of transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) . This mechanism of action makes it a valuable chemical probe for studying immunology and oncology in both cellular and animal models of disease.
CAS Number
444287-56-3
Product Name Alternative
E3 ligase-recruiting Moiety, E3 ligase Ligand 23, E-3 ligase Ligand 23, Cereblon, Aiolos, Inhibitor, Ligand for E3 Ligase, LigandforE3Ligase, Ligands for E3 Ligase, inhibit, Ikaros, ubiquitin proteasome
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Purity
98.49% (May vary between batches)
Solubility
DMSO:55 mg/mL (151.36 mM)
Smiles
N (CC1=CC=CC=C1) C2=C3C (C (=O) N (C3=O) C4C (=O) NC (=O) CC4) =CC=C2
Molecular Formula
C20H17N3O4
Molecular Weight
363.37
Storage Conditions
-20°C
Notes
For research use only.

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