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Seneciphylline

CAT: 0013-GTR19166802-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166802-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Seneciphylline is a mutagenic and hepatotoxic pyrrolizidine alkaloid, shown to transfer into rat milk. It modulates key hepatic detoxification enzymes, inducing epoxide hydrolase and glutathione-S-transferase while suppressing cytochrome P-450. This compound is used in toxicology research to study metabolic activation, detoxification pathways, and chemical hepatotoxicity in vitro and in vivo.
CAS Number
480-81-9
Product Name Alternative
Inhibit, Inhibitor, Gutathione S-transferase, GST, GSTs, Glutathione transferases, epoxide, hydrase, CYPs, cytochrome, Cytochrome P450, alkaloid, P-450, P450, pyrrolizidine, Seneciphylline, Toxic
Field of Research
Metabolism Research
Purity
99.53% (May vary between batches)
Solubility
DMSO:3.34 mg/mL (10.02 mM)
Smiles
[H][C@]12CCN3CC=C (COC (=O) [C@] (C) (O) C (=C) C\C (=C\C) C (=O) O1) [C@]23[H]
Molecular Formula
C18H23NO5
Molecular Weight
333.38
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

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