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PD146176

CAT: 0013-GTR19166514-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166514-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PD146176 (NSC-168807) is a potent 15-lipoxygenase (15-LO) inhibitor, demonstrating a Ki of 197 nM in enzymatic assays. In vivo studies using aged 3xTg-AD mice show it can ameliorate Alzheimer's-like pathology, including cognitive deficits and amyloidosis, by promoting autophagic clearance mechanisms.
CAS Number
4079-26-9
Product Name Alternative
Cells, cognitive, amyloidosis, Autophagy, brain, 15-LO, NSC-168807, NSC168807, PD146176, PD-146176, PD 146176, pathology, mice, NSC 168807, inhibit, impairment, Ferroptosis, IC21, Inhibitor, reticulocyte, tau, rabbit, triple, transgenic
Field of Research
Cell Biology, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (8.43 mM) ; H2O:< 0.1 mg/mL (insoluble) ; DMSO:25 mg/mL (105.34 mM)
Smiles
C1Sc2ccccc2-c2[nH]c3ccccc3c12
Molecular Formula
C15H11NS
Molecular Weight
237.32
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
M24370-01PD146176
MBS387761-01PD146176 (NSC168807)
HY-103157R-01PD146176 (Standard)
A13347-50PD146176 (NSC168807) 50mg
A13347-5PD146176 (NSC168807) 5mg
A13347-100PD146176 (NSC168807) 100mg
A13347-25PD146176 (NSC168807) 25mg
A13347-10PD146176 (NSC168807) 10mg
A13347-10mM-DPD146176 (NSC168807) 10mM * 1mL in DMSO

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