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Rosiptor

CAT: 0013-GTR19166353-03Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19166353-03Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rosiptor (AQX-1125) is an orally bioavailable, small-molecule activator of the SHIP1 phosphatase, which mediates its anti-inflammatory effects. It has been investigated in preclinical models for respiratory and dermatological conditions, demonstrating potential in both in vitro cellular assays and in vivo studies.
CAS Number
782487-28-9
Product Name Alternative
AQX 1125, AQX1125, AQX-1125, inhibit, Inhibitor, Rosiptor, SHIP1, Phosphatase
Field of Research
Metabolism Research
Purity
99.53% (May vary between batches)
Solubility
DMSO:145 mg/mL (451.01 mM)
Smiles
[H][C@@]12CCC (=C) [C@@]1 (C) CC[C@@] ([H]) ([C@H]2CN) [C@@]1 (C) CC[C@H] (O) C[C@@H]1CO
Molecular Formula
C20H35NO2
Molecular Weight
321.5
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

Chemical Information

Rosiptor

AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.

CAS Number782487-28-9
PubChem CID76965484
IUPAC Name(1S,3S,4R)-4-[(3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methylidene-3,3a,4,5,6,7-hexahydro-2H-inden-5-yl]-3-(hydroxymethyl)-4-methylcyclohexan-1-ol
Molecular FormulaC20H35NO2
Molecular Weight321.5
XLogP3
Topological Polar Surface Area66.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count23
Formal Charge0
Complexity465
SMILES
C[C@@]1(CC[C@@H](C[C@@H]1CO)O)[C@H]2CC[C@]3([C@H]([C@@H]2CN)CCC3=C)C
InChI
InChI=1S/C20H35NO2/c1-13-4-5-17-16(11-21)18(7-9-19(13,17)2)20(3)8-6-15(23)10-14(20)12-22/h14-18,22-23H,1,4-12,21H2,2-3H3/t14-,15+,16+,17+,18+,19-,20+/m1/s1
InChIKey
MDEJTPWQNNMAQF-BVMLLJBZSA-N
Chemical Structure
2D Structure
2D structure of Rosiptor
CAS: 782487-28-9
CID: 76965484
Formula: C20H35NO2
MW: 321.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight321.5
XLogP33
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass321.266779359
Monoisotopic Mass321.266779359
Topological Polar Surface Area66.5 Ų
Heavy Atom Count23
Formal Charge0
Complexity465
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA8092-5Rosiptor
HY-109011ARosiptor (acetate)
TQ0032L-01Rosiptor acetate
A19434-100Rosiptor 100mg
A19434-10Rosiptor 10mg
A19434-1Rosiptor 1mg
A19434-50Rosiptor 50mg
A19434-25Rosiptor 25mg
A19434-5Rosiptor 5mg
A19434-10mM-DRosiptor 10mM * 1mL in DMSO

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