Rosiptor acetate

• Target :

  Phosphatase|||Others

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast cells and inhibits human leukocyte chemotaxis. AQX-1125 suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.

• Smiles :

  C(C)(O)=O.C[C@@]1([C@@]2([C@@H](CN)[C@]3([C@](C)(CC2)C(=C)CC3)[H])[H])[C@@H](CO)C[C@@H](O)CC1

• Molecular Formula :

  C22H39NO4

• Molecular Weight :

  381.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  782487-29-0