Tiamulin

CAT: 0013-GTR19166091-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19166091-01Size:1 ml x 10 mM (in DMSO)

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Tiamulin is a semisynthetic derivative of the pleuromutilin class of antibiotics. It is widely used in research to study bacterial protein synthesis inhibition, particularly against Mycoplasma and Gram-positive pathogens, in both in vitro and in vivo experimental models.

CAS Number

55297-95-5

Product Name Alternative

Swine, Thiamutilin, Tiamulin, veterinary, Antibiotic, Bacterial, dysentery, enzootic, pneumonia, Inhibitor, inhibit

Field of Research

Infectious Disease & Virology

Purity

99.60% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.13 mM) ; DMSO:250 mg/mL (506.34 mM) ; Ethanol:2 mg/mL (4.05 mM) ; H2O:11 mg/mL (22.28 mM)

Smiles

[H][C@@]12C (=O) CC[C@]11CC[C@@H] (C) [C@@]2 (C) [C@@H] (C[C@@] (C) (C=C) [C@@H] (O) [C@@H]1C) OC (=O) CSCCN (CC) CC

Molecular Formula

C28H47NO4S

Molecular Weight

493.74

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Tiamulin

Tiamulin is a carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae. It has a role as an antibacterial drug. It is an organic sulfide, a carboxylic ester, a secondary alcohol, a carbotricyclic compound, a cyclic ketone, a tertiary amino compound, a tetracyclic diterpenoid and a semisynthetic derivative. It is functionally related to a Pleuromutilin.

CAS Number	55297-95-5
PubChem CID	656958
IUPAC Name	[(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-[2-(diethylamino)ethylsulfanyl]acetate
Molecular Formula	C28H47NO4S
Molecular Weight	493.7
XLogP	5.6
Topological Polar Surface Area	92.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	10
Heavy Atom Count	34
Formal Charge	0
Complexity	770

SMILES

CCN(CC)CCSCC(=O)O[C@@H]1C[C@@]([C@H]([C@@H]([C@@]23CC[C@H]([C@@]1([C@@H]2C(=O)CC3)C)C)C)O)(C)C=C

InChI

InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1

InChIKey

UURAUHCOJAIIRQ-QGLSALSOSA-N

Chemical Structure

2D Structure

CAS: 55297-95-5

CID: 656958

Formula: C28H47NO4S

MW: 493.7

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	493.7
XLogP3	5.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	10
Exact Mass	493.32258015
Monoisotopic Mass	493.32258015
Topological Polar Surface Area	92.1 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	770
Isotope Atom Count	0
Defined Atom Stereocenter Count	8
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
T091-100MG	Tiamulin
FD28262-01	Tiamulin fumarate
446004	Dehydro Tiamulin

Tiamulin

Chemical Information

Alternative Products

Popular Products