Products for Research Use Only

Simufilam dihydrochloride

CAT: 0013-GTR19165743-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165743-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Simufilam dihydrochloride is an orally bioavailable small molecule that selectively binds to misfolded filamin A (FLNA) in Alzheimer's disease research. It restores FLNA's normal function, which has been shown in experimental models to improve synaptic signaling and reduce neuroinflammation by disrupting pathological protein interactions.
CAS Number
2480226-06-8
Product Name Alternative
A7nAChR, inhibit, Inhibitor, PTI125, PTI-125, PTI125 Dihydrochloride, PTI-125 Dihydrochloride, PTI-125 dihydrochloride, PTI 125, PTI 125 Dihydrochloride, Simufilam, Simufilam dihydrochloride, Simufilam Dihydrochloride
Field of Research
Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:65 mg/mL (195.61 mM)
Smiles
[H]Cl.O=C1N (CC2=CC=CC=C2) C3 (CCN (C) CC3) NC1.[H]Cl
Molecular Formula
C15H23Cl2N3O
Molecular Weight
332.3
Storage Conditions
-20°C
Notes
For research use only.