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JNJ-63576253

CAT: 0013-GTR19165676-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19165676-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-63576253 is a clinical-stage small molecule androgen receptor (AR) antagonist active against both wild-type and F877L-mutant forms, targeting castration-resistant prostate cancer (mCRPC) . It is utilized in preclinical research to investigate AR signaling and resistance mechanisms in relevant in vitro and in vivo models.
CAS Number
2110428-64-1
Product Name Alternative
CRPC, castration, cancer, androgen, Androgen Receptor, AndrogenReceptor, Inhibitor, JNJ 63576253, inhibit, JNJ63576253, JNJ-63576253, mutant, LNCaP, prostate, resistant, wild-type, TRC 253, TRC253, TRC-253
Field of Research
Metabolism Research
Purity
98.71% (May vary between batches)
Solubility
H2O:insoluble; DMSO:200 mg/mL (371.08 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.28 mM)
Smiles
Cl.FC (F) (F) c1cc (cnc1C#N) N1C (=S) N (c2ccc (OC3CCNCC3) nc2) C2 (CCC2) C1=O
Molecular Formula
C23H22ClF3N6O2S
Molecular Weight
538.97
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
KJD42864-01JNJ-63576253
A22530-100JNJ-63576253 100mg
A22530-10JNJ-63576253 10mg
207173JNJ-63576253 HCl
A22530-25JNJ-63576253 25mg
A22530-2JNJ-63576253 2mg
A22530-200JNJ-63576253 200mg
A22530-50JNJ-63576253 50mg
A22530-5JNJ-63576253 5mg
S9900-01JNJ-63576253 (TRC-253)

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