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Dabrafenib Mesylate

CAT: 0013-GTR19166135-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19166135-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dabrafenib Mesylate is a potent and selective B-Raf inhibitor, with IC50 values of 0.6 nM for RafV600E and 5.0 nM for c-Raf. It is widely used in preclinical research to investigate targeted therapies for BRAF-mutant cancers in both cellular assays and animal models.
CAS Number
1195768-06-9
Product Name Alternative
Raf kinases, Raf, Dabrafenib, Dabrafenib Mesylate, GSK 2118436, GSK 2118436 Mesylate, GSK 2118436B, GSK2118436, GSK-2118436, GSK2118436 Mesylate, GSK-2118436 Mesylate, Inhibitor, inhibit
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.45% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.36 mM) ; DMSO:85 mg/mL (138.06 mM)
Smiles
CS (O) (=O) =O.CC (C) (C) c1nc (c (s1) -c1ccnc (N) n1) -c1cccc (NS (=O) (=O) c2c (F) cccc2F) c1F
Molecular Formula
C24H24F3N5O5S3
Molecular Weight
615.67
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
HY-14660A-01Dabrafenib (Mesylate)
445709-01Dabrafenib Mesylate
HY-14660AR-01Dabrafenib (Mesylate) (Standard)
A15059-50Dabrafenib Mesylate 50mg
A15059-10Dabrafenib Mesylate 10mg
A15059-5Dabrafenib Mesylate 5mg
A15059-100Dabrafenib Mesylate 100mg
A15059-500Dabrafenib Mesylate 500mg
A15059-25Dabrafenib Mesylate 25mg
A3347-10Dabrafenib Mesylate (GSK-2118436)

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