Products for Research Use Only
RegisterLogin

AZ194

CAT: 0013-GTR19164797-04Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19164797-04Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This small molecule inhibitor targets the CRMP2-Ubc9-NaV1.7 complex, disrupting this protein-protein interaction. It is a valuable research tool for studying neuropathic pain mechanisms in both cellular and animal models, as it modulates sodium channel trafficking and neuronal excitability.
CAS Number
2241651-99-8
Product Name Alternative
Inhibit, Inhibitor, nociceptive neurotransmission, Na+ channels, Na channels, Nav1.7 channel, pain, antinociceptive effects, AZ 194, AZ194, AZ-194, CRMP2-Ubc9 interaction, Sodium Channel, SodiumChannel, sensory neurons
Field of Research
Pharmacology & Drug Discovery
Purity
99.61% (May vary between batches)
Solubility
DMSO:50 mg/mL (88.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.52 mM)
Smiles
COc1cc (ccc1OCc1cccc (F) c1) C (=O) N1CCC (CC1) c1nc2ccccc2n1Cc1cccc (F) c1
Molecular Formula
C34H31F2N3O3
Molecular Weight
567.62
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(4-(1-(3-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-((3-fluorobenzyl)oxy)-3-methoxyphenyl)methanone
CAS Number2241651-99-8
PubChem CID135290226
IUPAC Name[4-[(3-fluorophenyl)methoxy]-3-methoxyphenyl]-[4-[1-[(3-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-1-yl]methanone
Molecular FormulaC34H31F2N3O3
Molecular Weight567.6
XLogP6.4
Topological Polar Surface Area56.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Heavy Atom Count42
Formal Charge0
Complexity873
SMILES
COC1=C(C=CC(=C1)C(=O)N2CCC(CC2)C3=NC4=CC=CC=C4N3CC5=CC(=CC=C5)F)OCC6=CC(=CC=C6)F
InChI
InChI=1S/C34H31F2N3O3/c1-41-32-20-26(12-13-31(32)42-22-24-7-5-9-28(36)19-24)34(40)38-16-14-25(15-17-38)33-37-29-10-2-3-11-30(29)39(33)21-23-6-4-8-27(35)18-23/h2-13,18-20,25H,14-17,21-22H2,1H3
InChIKey
HDKZBBHJFURFLF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (4-(1-(3-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-((3-fluorobenzyl)oxy)-3-methoxyphenyl)methanone
CAS: 2241651-99-8
CID: 135290226
Formula: C34H31F2N3O3
MW: 567.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight567.6
XLogP36.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Exact Mass567.23334818
Monoisotopic Mass567.23334818
Topological Polar Surface Area56.6 Ų
Heavy Atom Count42
Formal Charge0
Complexity873
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19172023-01AZ191
GTR19160482-01AZ191

Alternative Products

CatalogName
HY-145169-01AZ194

Popular Products