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GSK3685032

CAT: 0013-GTR19164725-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164725-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK3685032 is a potent, selective, and reversible non-covalent inhibitor of DNMT1 (IC50 = 36 nM) . It induces DNA demethylation and gene reactivation, demonstrating robust anti-proliferative effects in cancer cell lines and in vivo tumor models, making it a valuable tool for epigenetic and oncology research.
CAS Number
2170137-61-6
Product Name Alternative
Cancer, DNA Methyltransferase, DNA MTases, DNAMethyltransferase, DNMT1, DNMTs, GSK3685032, GSK-3685032, GSK 3685032, leukemia, GDM-1, lymphoma, Inhibitor, inhibit, multiple myeloma, MV4–11
Field of Research
Epigenetics & Chromatin
Purity
98.56% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.76 mM) ; DMSO:26.4 mg/mL (62.78 mM)
Smiles
CCc1c (C#N) c (SC (C (N) =O) c2ccccc2) nc (N2CCC (N) CC2) c1C#N
Molecular Formula
C22H24N6OS
Molecular Weight
420.53
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T9573-01GSK3685032

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