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GSK3685032

CAT: 0931-T9573-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9573-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2170137-61-6
Target
DNA Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9949
Bioactivity
GSK3685032 is a non-covalent and selective DNMT1 inhibitor (IC50 = 36 nM) . The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits cancer cell growth.
Smiles
CCc1c(C#N)c(SC(C(N)=O)c2ccccc2)nc(N2CCC(N)CC2)c1C#N
Molecular Formula
C22H24N6OS
Molecular Weight
420.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19164725-01GSK3685032

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