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LP-261

CAT: 0013-GTR19164704-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164704-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LP-261 is a colchicine-site tubulin inhibitor that arrests the cell cycle at the G2/M phase. It is a research tool for studying cytoskeleton dynamics and mechanisms of antimitotic agents in both in vitro cell-based assays and in vivo preclinical cancer models.
CAS Number
915412-67-8
Product Name Alternative
Cancer, BXPC-3, anti-mitotic, NCI-H522, MicrotubuleAssociated, Microtubule/Tubulin, Microtubule Associated, Jurkat, inhibit, LP261, LP-261, LP 261, H522, Inhibitor, MCF-7, SW-620, tubulin polymerization, tumor
Field of Research
Signal Transduction
Purity
99.76% (May vary between batches)
Solubility
DMSO:22 mg/mL (52.2 mM)
Smiles
COc1cc (ccn1) C (=O) c1cc (NS (C) (=O) =O) cc (c1) -c1cccc2[nH]ccc12
Molecular Formula
C22H19N3O4S
Molecular Weight
421.47
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

LP-261
CAS Number915412-67-8
PubChem CID15603282
IUPAC NameN-[3-(1H-indol-4-yl)-5-(2-methoxypyridine-4-carbonyl)phenyl]methanesulfonamide
Molecular FormulaC22H19N3O4S
Molecular Weight421.5
XLogP3.2
Topological Polar Surface Area110
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count30
Formal Charge0
Complexity710
SMILES
COC1=NC=CC(=C1)C(=O)C2=CC(=CC(=C2)C3=C4C=CNC4=CC=C3)NS(=O)(=O)C
InChI
InChI=1S/C22H19N3O4S/c1-29-21-13-14(6-8-24-21)22(26)16-10-15(11-17(12-16)25-30(2,27)28)18-4-3-5-20-19(18)7-9-23-20/h3-13,23,25H,1-2H3
InChIKey
YUVDELGTFILMBB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of LP-261
CAS: 915412-67-8
CID: 15603282
Formula: C22H19N3O4S
MW: 421.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight421.5
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass421.10962727
Monoisotopic Mass421.10962727
Topological Polar Surface Area110 Ų
Heavy Atom Count30
Formal Charge0
Complexity710
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BA4250-25LP-261
A22487-100LP-261 100mg
A22487-5LP-261 5mg
A22487-50LP-261 50mg
A22487-10LP-261 10mg
A22487-25LP-261 25mg
A2299-80AApolipoprotein Lp (a) (Apo Lp-a)
030400LPA (Apolipoprotein (a), LP, Lp (a) )
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