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Itopride hydrochloride

CAT: 0013-GTR19164240-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19164240-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Itopride hydrochloride is an AChE inhibitor (acetylcholinesterase) and D2DR inhibitor. (In Vitro) :Itopride hydrochloride has prokinetic effects on both the ileum and colon, which are regulated through inhibitory effects on AChE and antagonistic effects on dopamine D2 receptor.Itopride hydrochloride (0.1 nM-1 μM) significantly accelerats the propagation velocity of the peristalsis in ex guinea pig ileum. (In Vivo) :Itopride hydrochloride (30 mg/kg; p.o.) significantly accelerates gastric emptying compared with the vehicle group.Itopride hydrochloride (30 mg/kg; p.o.) displays Cmax of 358 ‰, T1/2 of 24.9 min.
CAS Number
122892-31-3
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 52mg/mL
Smiles
Cl.COC1=C (OC) C=C (C=C1) C (=O) NCC1=CC=C (OCCN (C) C) C=C1
Molecular Formula
C20H27CLN2O4
Molecular Weight
394.9
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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