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Paromomycin Sulfate

CAT: 0013-GTR19164140-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19164140-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Paromomycin Sulfate is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA. (In Vitro) :Paromomycin sulfate (500 μg/ml) reduces intracellular parasitic forms by 97.2% compared to control in Caco-2 cells and reduces the percentage of intracellular C. parvum forms by 99.5% in HCT-8 cells. (In Vivo) :Paromomycin sulfate (oral gavage; 50 mg/kg-200 mg/kg; once daily; for five consecutive days two weeks post infection) reduces the number of oocyst per gram of feces and intestine. It shows minimal focal inflammation in only 20% of the sections at 50 mg/kg from the intestines of mice infected with C. parvum and only 10% of focal inflammation at 200 mg/kg.
CAS Number
1263-89-4
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 100 mg/mL (140.11 mM)
Smiles
C1[C@H] ([C@@H] ([C@H] ([C@@H] ([C@H]1N) O[C@@H]2[C@@H] ([C@H] ([C@@H] ([C@H] (O2) CO) O) O) N) O[C@H]3[C@@H] ([C@@H] ([C@H] (O3) CO) O[C@@H]4[C@@H] ([C@H] ([C@@H] ([C@@H] (O4) CN) O) O) N) O) O) N.OS (=O) (=O) O
Molecular Formula
C23H47N5O18S
Molecular Weight
713.71
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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Alternative Products

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B1808-50Paromomycin Sulfate
HY-B0956-01Paromomycin (sulfate)

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