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AKT inhibitor

CAT: 0013-GTR19164105-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164105-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM (biochemical assay), and 0.31 nM (cell function assay) ; shows >900-fold selectivity over PKA; excellent PK profiles and effective in in vivo models of xenograft tumor.
CAS Number
1004990-28-6
Product Name Alternative
AKT protein kinase inhibitor
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC[C@]1 (N) CN (C2=C3C (NC=C3CC) =NC=N2) CC1) C4=CC=C (F) C=C4F
Molecular Formula
C20H22F2N6O
Molecular Weight
400.4251
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, N-[[ (3S) -3-amino-1- (5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl) -3-pyrrolidinyl]methyl]-2,4-difluoro-

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