Products for Research Use Only
RegisterLogin

3PO (b)

CAT: 0013-GTR19163834-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19163834-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor, reduces glycolytic flux and suppresses glucose uptake. Inhibits endothelial cell proliferation and causes G2/M cell cycle arrest in vitro. Attenuates vessel sprouting and tumor growth in vivo. Amplifies the antiangiogenic effect of VEGFR blockade.3PO may be useful agents in combination with other drugs that inhibit Y cell proliferation. PFKFB3 inhibitors suppress glucose uptake, which in turn causes an increase in autophagy. The addition of selective inhibitors of autophagy to 3PO and its more potent derivatives may prove useful as rational combinations for the treatment of Y.
CAS Number
13309-08-5
Purity
>98% (HPLC)
Solubility
DMSO: > 10 mM
Smiles
C1=CC (=CN=C1) /C=C/C (=O) C2=CC=NC=C2
Molecular Formula
C13H10N2O
Molecular Weight
210.23
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Related Products

CatalogName
GTR19213717-013PO
GTR19172861-013PO
GTR19155645-013PO
GTR19172566-01(E) -3PO
GTR19319500Influenza B (B/Malaysia)
GTR19009424Asialog. GM2, B.b.
GTR19009421Asialog. GM1, B.b.
GTR19009419Monosialog. GM1, B.b.
GTR19009408Disialog. GD1b, B.b.
GTR19009429Trisialog. GT1b, B.b.

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
BCS81BioCoupler® Glass Set (8 oz) x1
E-EL-H1579ELISA kit for Human PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9)
E-EL-M0380ELISA kit for Mouse CDKN1B (Cyclin Dependent Kinase Inhibitor 1B)
EA-IP-017MProtein L Magnetic beads
E-KAB-0415Human CA9 Antibody Pair Set
E-EL-M2699ELISA kit for Mouse ACTN1 (Actinin Alpha 1)
E-EL-H1851ELISA kit for Human DSG1 (Desmogleins 1)

Popular Products