Products for Research Use Only

3PO

CAT: 0013-GTR19155645-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19155645-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM) . It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.
CAS Number
18550-98-6
Purity
>98% (HPLC)
Solubility
DMSO:113mg/ml (537.51mM) ; Ethanol:11 mg/mL (52.32 mM) ; Water:Insoluble
Smiles
O=C (/C=C/c1cnccc1) c1ccncc1
Molecular Formula
C13H10N2O
Molecular Weight
210.23
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.