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Duloxetine hydrochloride

CAT: 0013-GTR19163739-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163739-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Duloxetine hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor . (In Vitro) :Duloxetine ((S) -Duloxetine hydrochloride) (sold under the brand names Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela, Dulane) is a serotonin-norepinephrine reuptake inhibitor (SNRI) manufactured and marketed by Eli Lilly. It is prescribed for major depressive disorder and generalized anxiety disorder (GAD) . Duloxetine also has approval for use in osteoarthiritis and musculoskeletal pain. Duloxetine failed the US approval for stress urinary incontinence amidst concerns over liver toxicity and suicidal events; however, it was approved for this indication in Europe, where it is recommended as an add-on medication in stress urinary incontinence instead of surgery. It can also relieve the symptoms of painful peripheral neuropathy, particularly diabetic neuropathy, and it is used to control the symptoms of fibromyalgia. The main uses of duloxetine are in major depressive disorder, general anxiety disorder, stress urinary incontinence, painful peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain associated with osteoarthritis and chronic lower back pain. It is being studied for various other indications.
CAS Number
136434-34-9
Product Name Alternative
LY248686
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 67 mg/mL (200.67 mM)
Smiles
CNCC[C@@H] (C1=CC=CS1) OC2=CC=CC3=CC=CC=C32
Molecular Formula
C18H20ClNOS
Molecular Weight
333.88
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(3S) -N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine

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