MG-101

CAT: 0013-GTR19163667-01Size: 200 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19163667-01Size:200 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

A potent inhibitor of cysteine proteases including calpain I (Ki= 190 nM), calpain II (Ki= 220 nM), cathepsin B (Ki= 150 nM) and cathepsin L (Ki= 500 pM) ; activates p53-dependent apoptosis in tumor cell lines; increases activated p53, p21 and caspase levels and promotes cell cycle arrest through inhibition of cyclin D degradation in vitro.

CAS Number

110044-82-1

Product Name Alternative

Calpain inhibitor I | ALLN

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

CC (C) C[C@H] (NC (C) =O) C (N[C@@H] (CC (C) C) C (N[C@H] (CCCC) C=O) =O) =O

Molecular Formula

C20H37N3O4

Molecular Weight

383.5255

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

L-Leucinamide, N-acetyl-L-leucyl-N-[ (1S) -1-formylpentyl]-

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