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MW-150

CAT: 0013-GTR19163924-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163924-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM; effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models; also can selectively modulate neuroinflammatory responses associated with pathology progression.
CAS Number
1628502-91-9
Product Name Alternative
MW01-18-150SRM | MW 150 | MW150
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 40 mg/mL (104.86 mM)
Smiles
CN1CCN (CC1) C2=NN=C (C (=C2) C3=CC=NC=C3) C4=CC5=CC=CC=C5C=C4
Molecular Formula
C24H23N5
Molecular Weight
381.483
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6- (4-methylpiperazin-1-yl) -3- (naphthalen-2-yl) -4- (pyridin-4-yl) pyridazine

Chemical Information

Mw-150
CAS Number1628502-91-9
PubChem CID86270361
IUPAC Name6-(4-methylpiperazin-1-yl)-3-naphthalen-2-yl-4-pyridin-4-ylpyridazine
Molecular FormulaC24H23N5
Molecular Weight381.5
XLogP3.6
Topological Polar Surface Area45.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count29
Formal Charge0
Complexity513
SMILES
CN1CCN(CC1)C2=NN=C(C(=C2)C3=CC=NC=C3)C4=CC5=CC=CC=C5C=C4
InChI
InChI=1S/C24H23N5/c1-28-12-14-29(15-13-28)23-17-22(19-8-10-25-11-9-19)24(27-26-23)21-7-6-18-4-2-3-5-20(18)16-21/h2-11,16-17H,12-15H2,1H3
InChIKey
CIIVUDIZZJLXCN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Mw-150
CAS: 1628502-91-9
CID: 86270361
Formula: C24H23N5
MW: 381.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight381.5
XLogP33.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass381.19534575
Monoisotopic Mass381.19534575
Topological Polar Surface Area45.2 Ų
Heavy Atom Count29
Formal Charge0
Complexity513
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BA3636-25MW-150
MBS5799840MW-150 hydrochloride
A18798-1MW-150 1mg
A18798-50MW-150 50mg
A18798-25MW-150 25mg
A18798-100MW-150 100mg
A18798-10MW-150 10mg
A18798-500MW-150 500mg
A18798-5MW-150 5mg
HY-120111BMW-150 dihydrochloride dihydrate

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