Products for Research Use Only
RegisterLogin

Avasimibe

CAT: 0013-GTR19163558-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19163558-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Avasimibe (CI-1011, PD-148515) is a potent, selective inhibitor of acyl-CoA: cholesterol O-acyl transferase (ACAT) with IC50 of 60 nM; potently reduces plasma cholesterol in chow-fed rats and in rabbits fed a cholesterol-free, casein-containing diet characterized by both hepatic overproduction of apo B-containing lipoproteins and delayed lipoprotein clearance; decreases both VLDL and LDL apolipoprotein B production in miniature pigs; synergistically reduces cholesteryl ester content in THP-1 macrophages combined with Atorvastatin, Dyslipidemia Phase 3 Discontinued.
CAS Number
166518-60-1
Product Name Alternative
CI-1011 | PD-148515 | CI1011 | PD148515 | CI 1011 | PD 148515
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 28 mg/mL
Smiles
C1 (C (C) C) cc (cc (c1CC (NS (Oc1c (cccc1C (C) C) C (C) C) (=O) =O) =O) C (C) C) C (C) C
Molecular Formula
C29H43NO4S
Molecular Weight
501.72102
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Sulfamic acid, N-[2-[2,4,6-tris (1-methylethyl) phenyl]acetyl]-, 2,6-bis (1-methylethyl) phenyl ester

Alternative Products

CatalogName
A4318-200Avasimibe

Popular Products