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SB-225002

CAT: 0013-GTR19163428-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19163428-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective non-peptide CXCR2 antagonist with IC50 of 22 nM; displays >150-fold selectivity over CXCR1; potently inhibits human and rabbit neutrophil chemotaxis induced by both IL-8 and GROalpha in vitro; selectively blocks IL-8-induced neutrophil margination in rabbits.
CAS Number
182498-32-4
Product Name Alternative
SB225002
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC1=CC=C ([N+] ([O-]) =O) C=C1O) NC2=CC=CC=C2Br
Molecular Formula
C13H10BrN3O4
Molecular Weight
352.1402
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Urea, N- (2-bromophenyl) -N'- (2-hydroxy-4-nitrophenyl) -

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B3282-25SB-225002
ALX-270-478-M005SB 225002
TBI2850-25MGSB-225002, CXCR2 antagonist
217783SB-277011-A Dihydrochloride (SB277011A, SB 277011A, Dopamine D3 Receptor Antagonist, SB-277011-A, SB-277011A)
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