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Polymyxin B sulfate

CAT: 0013-GTR19163296Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19163296Size:1 g
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Description
Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic. (In Vitro) :Polymyxin B Sulfate shows antibacterial activities with MICs of 0.5 mg/l for E. coli strain IH3080. (In Vivo) :Polymyxin B Sulfate (0.5-120 mg/kg; s.c.) shows antibacterial activities in thigh or lung infection mouse model.Polymyxin B Sulfate (2 mg/kg, s.c.) shows potent in mouse bactericidal effect against E. coli strain IH3080.
CAS Number
1405-20-5
Product Name Alternative
Aerosporin | Mastimyxin
Purity
>98% (HPLC)
Solubility
Water: 25 mg/mL
Smiles
CCC (C) CCCCC (=O) NC (CCN) C (=O) NC (C (C) O) C (=O) NC (CCN) C (=O) NC1CCNC (=O) C (NC (=O) C (NC (=O) C (NC (=O) C (NC (=O) C (NC (=O) C (NC1=O) CCN) CC2=CC=CC=C2) CC (C) C) CCN) CCN) C (C) O.OS (=O) (=O) O
Molecular Formula
C56H100N16O17S
Molecular Weight
1301.56
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N-[ (2S) -4-amino-1-[[ (2S,3R) -1-[[ (2S) -4-amino-1-oxo-1-[[ (3S,6S,9S,12S,15R,18R,21S) -6,9,18-tris (2-aminoethyl) -15-benzyl-3-[ (1R) -1-hydroxyethyl]-12- (2-methylpropyl) -2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide; sulfuric acid

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Alternative Products

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