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Polymyxin B2 sulfate

CAT: 0931-T83903-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T83903-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
108965-69-1
Target
Others, Antibiotic, Antibacterial
Related Pathways
Others, Microbiology/Virology
Bioactivity
Polymyxin B2, a significant component of polymyxin B, is an antibiotic cationic lipopeptide initially derived from B. polymyxa. This compound effectively inhibits P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloacae strains, exhibiting minimum inhibitory concentrations (MICs) of 1-2, 0.5-1, 0.25-0.5, and 0.25-1 μg/ml, respectively. Notably, in a mouse model of P. aeruginosa bloodstream infection, administration of polymyxin B2 at a dosage of 4 mg/kg has been shown to decrease the number of colony-forming units (CFUs) in the blood.
Smiles
NCC[C@@H](C(N[C@H]1CCNC([C@@]([C@H](O)C)([H])NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC1=O)CCN)=O)CC2=CC=CC=C2)=O)CC(C)C)=O)CCN)=O)CCN)=O)=O)=O)NC([C@H]([C@H](O)C)NC([C@@H](NC(CCCCC(C)C)=O)CCN)=O)=O.O=S(O)(O)=O
Molecular Formula
C55H96N16O13.XH2SO4
Molecular Weight
1189.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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