Bruceine E

• Description :

  Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753) ) -induced diabetic rats at lower dose[2].

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Natural Products

• Related Pathways :

  Others

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/bruceine-e.html

• Purity :

  97.32

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC([C@](C[C@@](O1)2[H])3[H])=C[C@H](O)[C@@H](O)[C@]3(C)[C@]4([H])[C@]2(CO[C@@]5([C@@H](O)[C@@H]4O)C)[C@@]5(O)[C@@H](O)C1=O

• Molecular Formula :

  C20H28O9

• Molecular Weight :

  412.43

• References & Citations :

  [1]Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188.|[2]Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17 (1) :94. Published 2017 Feb 6.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [21586-90-3]