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NAcM-OPT

CAT: 0013-GTR19162812-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162812-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NAcM-OPT is a specific, reversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 79 nM in TR-FRET assays; also inhibits DCN2, but has no activity against DCN3, DCN4, or DCN5; inhibits NEDD8 ligation in vitro and in cells, and suppress anchorage-independent growth of a cell line with DCN1 amplification.
CAS Number
2089293-61-6
Product Name Alternative
NAcM-OPT | NAcM OPT | NAcMOPT
Purity
>98% (HPLC)
Solubility
DMSO: 100 mg/mL, 230.20 mM; Water: Insoluble (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (NC1=CC=C (Cl) C (Cl) =C1) N (CC2=CC=CC=C2) C3CCN (CCCC) CC3
Molecular Formula
C23H29Cl2N3O
Molecular Weight
434.405
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-benzyl-1- (1-butylpiperidin-4-yl) -3- (3,4-dichlorophenyl) urea

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BA7382-10NAcM-OPT
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A19646-100NAcM-OPT 100mg
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A19646-50NAcM-OPT 50mg
A19646-5NAcM-OPT 5mg
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