NAcM-OPT (hydrochloride)
CAT:
804-HY-111505A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NAcM-OPT (hydrochloride)
- CAS Number: 2416146-10-4
- UNSPSC Description: NAcM-OPT (hydrochloride) is a protein interaction inhibitor. NAcM-OPT (hydrochloride) can disrupt the interaction between DCN1 and UBC12, with an IC50 value of 80 nM. NAcM-OPT (hydrochloride) can protect keratinocytes from H2O2-induced cell damage by promoting autophagy[1][2].
- Target Antigen: Autophagy
- Type: Reference compound
- Related Pathways: Autophagy
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/nacm-opt-hydrochloride.html
- Smiles: O=C(NC1=CC=C(Cl)C(Cl)=C1)N(C2CCN(CCCC)CC2)CC3=CC=CC=C3.Cl
- Molecular Weight: 470.86
- References & Citations: [1]Fang Y, et al. Targeting the DCN1-UBC12 protein-protein interaction: novel approaches and future directions. Future Med Chem. 2019 Nov;11(22):2869-2871.|[2]Xiong R, et al. NAcM-OPT protects keratinocytes from H2O2-induced cell damage by promoting autophagy. Ann N Y Acad Sci. 2024 Jul;1537(1):155-167.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported