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Celastrol

CAT: 0013-GTR19163435-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19163435-01Size:200 mg
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Description
Celastrol (Tripterin), a bioactive compound from Thunder God Vine, is a potent proteasome inhibitor that preferentially targets the 20S chymotrypsin-like activity (IC50 = 2.5 μM) and inhibits the 26S proteasome in prostate cancer cells. It induces apoptosis, promotes accumulation of ubiquitinated proteins and proteasome substrates, suppresses AR expression, and demonstrates significant tumor growth inhibition in vivo.
CAS Number
34157-83-0
Product Name Alternative
Tripterin
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CC1=C (C (=O) C=C2C1=CC=C3C2 (CCC4 (C3 (CCC5 (C4CC (CC5) (C) C (=O) O) C) C) C) C) O
Molecular Formula
C29H38O4
Molecular Weight
450.6096
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
24,25,26-Trinoroleana-1 (10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9.beta.,13.alpha.,14.beta.,20.alpha.) -

Alternative Products

CatalogName
200694Celastrol

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