TAK-779

CAT: 0013-GTR19162769-01Size: 200 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19162769-01Size:200 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

TAK-779 is a potent, specific, nonpeptide CCR5 antagonist with Kd of 0.45 nM, antagonizes CCR2b to a lesser extent (27 nM) but does not affect CCR1, CCR3, or CCR4; also blocks the binding of macrophage inflammatory protein 1α and macrophage inflammatory protein 1β to the cells with an IC50 of 1.0 nM; TAK-779 displays highly potent and selective inhibition of the replication of macrophage (M) -tropic HIV-1 (Ba-L strain) in both MAGI-CCR5 cells and PBMCs with EC50 of 1.2 and 3.7 nM, respectively.HIV Infection Discontinued.

CAS Number

229005-80-5

Product Name Alternative

TAK779 | TAK 799 | Takeda 779

Field of Research

Epigenetics & Chromatin

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 27 mg/mL

Smiles

CC1=CC=C (C=C1) C2=CC3=C (CCCC (=C3) C (=O) NC4=CC=C (C=C4) C[N+] (C) (C) C5CCOCC5) C=C2.[Cl-]

Molecular Formula

C33H39ClN2O2

Molecular Weight

531.1

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2H-Pyran-4-aminium, N-[[4-[[[6,7-dihydro-2- (4-methylphenyl) -5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N, N-dimethyl-, chloride (1:1)

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GTR19210485-01	TAK-233
GTR19208963-01	TAK-137
GTR19204183-01	TAK-778
GTR19203050-01	TAK-220
GTR19174126-01	TAK-243

Alternative Products

Catalog	Name
BA1898-5	TAK-779
4340/10	TAK 779
A13846-10	TAK-779 10mg
A13846-5	TAK-779 5mg
A13846-50	TAK-779 50mg
A13846-25	TAK-779 25mg
A13846-100	TAK-779 100mg
A13846-1	TAK-779 1mg
A13846-10mM-D	TAK-779 10mM * 1mL in DMSO
T7616	A 779

TAK-779

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