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TR-14035

CAT: 0013-GTR19162569-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162569-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, orally bioavailable, dual α4β7/α4β1 integrin antagonist with IC50 of 7/87 nM; blocks the binding of human α4β7 to an (125) I-MAdCAM-Ig fusion protein with IC50 of 0.75 nM; suppresses antigen-induced lung interleukin (IL) -5 mRNA upregulation, inhibits the leukocyte rolling flux, adhesion and emigration induced by IL4 in rats.Asthma Phase 1 Discontinued.
CAS Number
232271-19-1
Product Name Alternative
TR 14035 | TR14035
Purity
>98% (HPLC)
Solubility
DMSO:≥ 41 mg/mL
Smiles
O=C (O) [C@H] (CC1=CC=C (C2=C (OC) C=CC=C2OC) C=C1) NC (C3=C (Cl) C=CC=C3Cl) =O
Molecular Formula
C24H21Cl2NO5
Molecular Weight
474.3333
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
[1,1'-Biphenyl]-4-propanoic acid, α-[ (2,6-dichlorobenzoyl) amino]-2',6'-dimethoxy-, (αS) -

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Alternative Products

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S0314-5mgTR-14035
6908/10TR 14035
A17118-200TR-14035 200mg
A17118-100TR-14035 100mg
A17118-50TR-14035 50mg
A17118-25TR-14035 25mg
A17118-10TR-14035 10mg
A17118-5TR-14035 5mg
A17118-1TR-14035 1mg
A17118-10mM-DTR-14035 10mM * 1mL in DMSO

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