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Telaprevir

CAT: 0013-GTR19162273-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162273-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective, covalent, orally bioavailable inhibitor of HCV NS3/4A protease with Ki of 7 nM; demonstrates excellent antiviral activity both in genotype 1b HCV replicon cells (IC50=354 nM) and in human fetal hepatocytes (IC50=280 nM) ; shows excellent viral inhibition in vivo with favorable pharmacokinetic profile.HCV Infection Approved.
CAS Number
402957-28-2
Product Name Alternative
VX-950 | VX950 | VX 950
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C ([C@@H]1[C@] (CCC2) ([H]) [C@]2 ([H]) CN1C ([C@@H] (NC ([C@H] (C3CCCCC3) NC (C4=NC=CN=C4) =O) =O) C (C) (C) C) =O) N[C@@H] (CCC) C (C (NC5CC5) =O) =O
Molecular Formula
C36H53N7O6
Molecular Weight
679.8493
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Cyclopenta[c]pyrrole-1-carboxamide, (2S) -2-cyclohexyl-N- (2-pyrazinylcarbonyl) glycyl-3-methyl-L-valyl-N-[ (1S) -1-[2- (cyclopropylamino) -2-oxoacetyl]butyl]octahydro-, (1S,3aR,6aS) -

Alternative Products

CatalogName
C07879-10mM/1mLTelaprevir

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