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Flumequine

CAT: 0013-GTR19162228-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162228-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. (In Vitro) :Flumequine (R-802) is a topoisomerase II inhibitor, with an IC50 of 3.92 μg/mL, and less potently inhibits Gyrase, with an IC50 of 1764 μg/mL. Flumequine (0-625 μg/mL) increases migration of nuclear DNA from CHL cells. Flumequine (R-802) inhibits Spanish field isolates of B. hyodysenteriae with MIC50 and MIC90 of 50 and 100 μg/mL, and MBC50 and MBC90 of 50, 200 μg/mL, respectively. Flumequine (R-802) suppresses A. salmonicida isolates with MIC ranging from 0.06 to 32 μg/mL. (In Vivo) :Flumequine (R-802) (0-500 mg/kg, p.o.) causes dose-related DNA damage in the stomach, colon, and urinary bladder of mice, 1 and 3 h but not 24 h after its administration.
CAS Number
42835-25-6
Product Name Alternative
(±) -Flumequine
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 3 mg/mL (11.48 mM)
Smiles
O=C (C (C1=O) =CN2C (C) CCC3=C2C1=CC (F) =C3) O
Molecular Formula
C14H12FNO3
Molecular Weight
261.25
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
7-Fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9 (13) -tetraene-3-carboxylic acid

Alternative Products

CatalogName
S3181-10mgFlumequine

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