Products for Research Use Only
RegisterLogin

Prednisone

CAT: 0013-GTR19162134-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19162134-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound. (In Vivo) :Prednisone (intramuscular injection, 10 mg/kg once a day, on days 4 to 13) reduces the survival rate on days lower than the control group in BALB/c mice with encephalomyocarditis virus myocarditis. Besides, myocardial virus titers reaches a maximum on day 4, but there is no antibody titer, and on day 8 virus titers remains elevated and antibody titers is also high. On day 10, antibody titers are significantly lower than controls, while viral titers remains significantly elevated.Prednisone (5 mg/kg, intragastrically administration, daily) can cause changes in FA metabolism in SLE mouse (MRL/lpr) model.
CAS Number
53-03-2
Product Name Alternative
1,2-Dehydrocortisone | NSC 10023
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 71 mg/mL (198.08 mM)
Smiles
CC12CC (=O) C3C (C1CCC2 (C (=O) CO) O) CCC4=CC (=O) C=CC34C
Molecular Formula
C21H26O5
Molecular Weight
358.43
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(8S,9S,10R,13S,14S,17R) -17-hydroxy-17- (2-hydroxyacetyl) -10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

Chemical Information

Prednisone

Prednisone is a synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid. It has a role as an anti-inflammatory drug, an antineoplastic agent, an immunosuppressive agent, an adrenergic agent and a prodrug. It is a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone, a glucocorticoid, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, an 11-oxo steroid, a C21-steroid and a 3-oxo-Delta(1),Delta(4)-steroid.

CAS Number53-03-2
PubChem CID5865
IUPAC Name(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
Molecular FormulaC21H26O5
Molecular Weight358.4
XLogP1.5
Topological Polar Surface Area91.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count26
Formal Charge0
Complexity764
SMILES
C[C@]12CC(=O)[C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C
InChI
InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChIKey
XOFYZVNMUHMLCC-ZPOLXVRWSA-N
Chemical Structure
2D Structure
2D structure of Prednisone
CAS: 53-03-2
CID: 5865
Formula: C21H26O5
MW: 358.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight358.4
XLogP31.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass358.17802393
Monoisotopic Mass358.17802393
Topological Polar Surface Area91.7 Ų
Heavy Atom Count26
Formal Charge0
Complexity764
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19174409-01Prednisolone
GTR19202638-01NO-prednisolone
GTR19161845-01Prednisolone
GTR19205098-01Prednisolone farnesylate
GTR19176221-01Prednisolone acetate
GTR19205080-01Prednisolone Tebutate
GTR19204244-01Prednisolone hemisuccinate
GTR19272962-01Prednisolone sodium succinate
GTR19246587-016-Dehydro prednisolone
GTR192325296β-hydroxy Prednisolone

Alternative Products

CatalogName
TRC-P703780-25MGPrednisone

Popular Products