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Rapamycin

CAT: 0013-GTR19162130-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19162130-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A macrolide compound that has potent immunosuppressive and antiproliferative properties by inhibiting mTOR (IC50=0.1 nM) .Other Indication Approved (In Vitro) :Rapamycin (GMP) (1 nM; 2-3 weeks) induces in vitro differentiation of human embryonic stem cell (hESCs) into mineralized osteoblasts.Rapamycin (GMP) (1 nM; 2-3 weeks) enhances the osteoblastic differentiation of human embryoid bodies (hEBs) .Rapamycin (GMP) (20 nM; 4 h) serum-dependently promotes vascular smooth muscle cells (VSMCs) differentiation.Rapamycin (GMP) induces osteoblastic differentiation in rat osteoblast-like osteosarcoma cells.
CAS Number
53123-88-9
Product Name Alternative
Sirolimus
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 28 mg/mL
Smiles
C[C@@H] (C ([C@H] (OC) [C@H] (O) /C (C) =C/[C@@H] (C) C (C[C@@H] ([C@H] (C) C[C@@H]1CC[C@@H] (O) C (OC) C1) OC2=O) =O) =O) C[C@H] (C) /C=C/C=C/C=C (C) /[C@@H] (OC) C[C@H]3O[C@] (C (C (N4[C@H]2CCCC4) =O) =O) (O) [C@H] (C) CC3
Molecular Formula
C51H79NO13
Molecular Weight
914.1719
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Rapamycin

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