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Trolox

CAT: 0013-GTR19162125-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162125-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It is an antioxidant like vitamin E and it is used in biological or biochemical applications to reduce oxidative stress or damage. (In Vitro) :Trolox has shown to protect mammalian cells from oxidative damage. Trolox is effective in preventing myocyte necrosis in cell culture studies and in a canine model of two hours of left anterior descending coronary artery (LAD) occlusion followed by four hours of reperfusion.Trolox could prevent oxidative stress-induced apoptosis in thymocytes. Pre- or posttreatment of cells with Trolox reduced H2O2-induced DNA fragmentation to control levels and below. .Trolox is a hydrophilic analogue of alpha-tocopherol and reported to scavenge peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes. Trolox prolongs substantially the survival of human ventricular myocytes and hepatocyte against oxyradicals generated with xanthine oxidase plus hypoxanthine, and prevented lysis of red cells exposed to an azo-initiator.
CAS Number
53188-07-1
Purity
>98% (HPLC)
Solubility
Soluble in Water
Smiles
O=C (C1 (C) CCC2=C (O1) C (C) =C (C) C (O) =C2C) O
Molecular Formula
C14H18O4
Molecular Weight
250.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

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