Trolox (GMP)

• Description:

  Trolox (GMP) is Trolox (HY-101445) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage[1][2].

• UNSPSC:

  12352211

• Hazard Statement:

  H315-H319-H401

• Target:

  Apoptosis; Ferroptosis; Reactive Oxygen Species (ROS)

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Cancer

• Smiles:

  O=C(C1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1)O

• Molecular Formula:

  C14H18O4

• Molecular Weight:

  250.29

• Precautions:

  P264-P273-P280-P302+P352-P305+P351+P338-P362+P364-P501

• References & Citations:

  [1]Mickle DA, et al. Myocardial salvage with trolox and ascorbic acid for an acute evolving infarction. Ann Thorac Surg. 1989 Apr;47 (4) :553-7.|[2]Forrest VJ, et al. Oxidative stress-induced apoptosis prevented by Trolox. Free Radic Biol Med. 1994 Jun;16 (6) :675-84.|[3]Wu TW, et al. The cytoprotective effect of Trolox demonstrated with three types of human cells. Biochem Cell Biol. 1990 Oct;68 (10) :1189-94.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  53188-07-1