Chlorotrianisene

CAT: 0013-GTR19161972-01Size: 500 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19161972-01Size:500 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Chlorotrianisene is a powerful synthetic, non-steroidal estrogen. (In Vitro) :Comparison of intracellular estrogen receptor (ER) affinities of Chlorotrianisene with respective rat uterine cytosolic ER affinities has initially suggested the potential for activation of ER as a mechanism of growth stimulation. Chlorotrianisene exhibits concentration dependent cell growth stimulation with an EC50 of 28 nM and a Ki of 500 nM in MCF-7 cells. (In Vivo) :The incubation of Chlorotrianisene with rat liver microsomes and NADPH generates a reactive intermediate which binds covalently to proteins. Intermediate may inactivate the uterine estrogen receptors (ER) . The incubation of Chlorotrianisene with rat liver microsomes and NADPH in the presence of rat uteri, under conditions which generate intermediate, markedly decreased the binding capacity of the ER for [3H]estradiol (E2) .

CAS Number

569-57-3

Product Name Alternative

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO: 10 mM

Smiles

COC1=CC=C (C=C1) C (=C (C2=CC=C (C=C2) OC) Cl) C3=CC=C (C=C3) OC

Molecular Formula

C23H21ClO3

Molecular Weight

380.86

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1-[1-chloro-2,2-bis (4-methoxyphenyl) ethenyl]-4-methoxybenzene

Alternative Products

Catalog	Name
B5912-5.1	Chlorotrianisene
A16446-250	Chlorotrianisene 250mg
A16446-100	Chlorotrianisene 100mg
HY-B2158S-01	Chlorotrianisene-d9
A16446-5	Chlorotrianisene 5mg
HY-B2158R	Chlorotrianisene (Standard)
A16446-50	Chlorotrianisene 50mg
A16446-10	Chlorotrianisene 10mg
C211361	Chlorotrianisene-d9 (trimethoxy-d9)
SD0020-25mg	Chlorotrianisene (Estrogen Receptor modulator)

Chlorotrianisene

Alternative Products

Popular Products