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Rifabutin

CAT: 0013-GTR19161643-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19161643-01Size:1 g
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Description
A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Bacterial Infection Approved (In Vitro) :Rifabutin is primarily bactericidal antibiotic drug used to treat tuberculosis. Its effect on bacteria is based on the DNA-dependent RNA polymerase blocking drug rifamycin S., a semi-synthetic derivative. It is effective, for example, in highly resistant mycobacteria, Gram-positive bacteria (and some are effective against Gram-negative bacteria), but also against Mycobacterium tuberculosis, M. leprae, and M. avium intracellulare. Rifabutin is an antibiotic; antitumor. Rifabutin interferes with HSP-90 molecular chaperone, enhances ubiquitination and protein degradation, and inactivates bacterial RNA polymerase.
CAS Number
72559-06-9
Product Name Alternative
Ansamycin | LM-427
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C1c2c (O) c (C) c3c (C4=O) c2C5=NC6 (CCN (CC (C) C) CC6) NC5=C1NC (/C (C) =C/C=C/[C@@H] ([C@H] (O) [C@H] ([C@@H] (O) [C@H] ([C@@H] ([C@H] (C) [C@@H] (OC) /C=C/O[C@]4 (O3) C) OC (C) =O) C) C) C) =O
Molecular Formula
C46H62N4O11
Molecular Weight
847.0047
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Spiro[9,4- (epoxypentadeca[1,11,13]trienimino) -2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26 (3H,9H) -trione, 16- (acetyloxy) -6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'- (2-methylpropyl) -, (9S,12E,14S,15R,16S,17R,18R,19

Alternative Products

CatalogName
B2126-5.1Rifabutin
RM-R090709-01Rifabutin Impurity 9 (Rifabutin N-Oxide)
TRC-N759265-10MGNitroso Rifabutin
A10790-50Rifabutin 50mg
C08023-100mgRifabutin (LM427)

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