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BAY 61-3606

CAT: 0013-GTR19161625-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161625-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src; inhibits not only degranulation (IC50=5-46 nM) but also lipid mediator and cytokine synthesis in mast cells; suppresses B cell receptor activation and receptors for Fc portion of IgG signaling in eosinophils and monocytes; suppresses antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema at 3 mg/kg in rats; orally bioavailable.Allergy Preclinical.
CAS Number
732983-37-8
Product Name Alternative
BAY61-3606
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (C1=CC=CN=C1NC2=NC (C3=CC=C (OC) C (OC) =C3) =CC4=NC=CN24) N
Molecular Formula
C20H18N6O3
Molecular Weight
390.3953
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- ((7- (3,4-dimethoxyphenyl) imidazo[1,2-c]pyrimidin-5-yl) amino) nicotinamide

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Alternative Products

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A3227-5BAY 61-3606
MBS579308BAY-61-3606
A3228-25BAY 61-3606 dihydrochloride
442151-01BAY 61-3606 Hydrochloride
A11320-100BAY 61-3606 100mg
A11320-25BAY 61-3606 25mg
A11320-1BAY 61-3606 1mg

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