Products for Research Use Only

Metadoxine

CAT: 0013-GTR19161596-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161596-01Size:500 mg
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Description
It is neurotransmitter stimulants. (In Vitro) :Simultaneous Metadoxine treatment notably inhibits adipogenic differentiation in a dose-dependent manner. Metadoxine treatment from day 4 through day 8 is required for inhibition of MDI-induced preadipocyte differentiation. Metadoxine prevents glutathione depletion and the increase in lipid peroxidation damage caused by ethanol and acetaldehyde in HepG2 cells. In hepatic stellate cells, Metadoxine prevents the increase in collagen and attenuated TNF-α secretion caused byacetaldehyde. Thus, Metadoxine could be useful in preventing the damage produced in early stages of alcoholic liver disease as it prevents the redox imbalance of the hepatocytes and prevents TNF-α induction, one of the earliest events in hepatic damage.
CAS Number
74536-44-0
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
CC1=NC=C (C (=C1O) CO) CO.C1CC (=O) N[C@@H]1C (=O) O
Molecular Formula
C8H11NO3·C5H7NO3
Molecular Weight
298.293
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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