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Metadoxine

CAT: 0804-HY-B1898-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1898-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway.
CAS Number
74536-44-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Metadoxine.html
Purity
99.88
Solubility
H2O : ≥ 155 mg/mL
Smiles
O=C(O)[C@H](CC1)NC1=O.OCC2=C(CO)C(O)=C(C)N=C2
Molecular Formula
C13H18N2O6
Molecular Weight
298.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Yang YM, et al. Metadoxine, an ion-pair of pyridoxine and L-2-pyrrolidone-5-carboxylate, blocks adipocyte differentiation in association with inhibition of the PKA-CREB pathway. Arch Biochem Biophys. 2009 Aug 15;488 (2) :91-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched

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