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Fexinidazole

CAT: 0013-GTR19161319-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19161319-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fexinidazole is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologically relevant active metabolites in vivo are the sulfoxide and sulfone. (In Vitro) :Fexinidazole (HOE 239) has two principal metabolites, sulfoxide and sulfone. They have shown trypanocidal activity in vitro with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml) range against all parasite strains tested. (In Vivo) :Fexinidazole (HOE 239; 20-50 mg/kg/day of IP or 25-100 mg/kg/day of PO; four consecutive days) has antitrypanosomal activities.
CAS Number
59729-37-2
Product Name Alternative
Fexinidazole | Hoe-239 | Hoe 239 | Hoe239
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
O=[N+] (C1=CN=C (COC2=CC=C (SC) C=C2) N1C) [O-]
Molecular Formula
C12H13N3O3S
Molecular Weight
279.31
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1-Methyl-2- ((p- (methylthio) phenoxy) methyl) -5-nitroimidazole

Alternative Products

CatalogName
HY-13801-01Fexinidazole
HY-13801R-01Fexinidazole (Standard)
A21274-25Fexinidazole 25mg
A21274-10Fexinidazole 10mg
A21274-200Fexinidazole 200mg
A21274-100Fexinidazole 100mg
A21274-5Fexinidazole 5mg
A21274-500Fexinidazole 500mg
A21274-50Fexinidazole 50mg
A21274-10mM-DFexinidazole 10mM * 1mL in DMSO

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