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Meropenem

CAT: 0013-GTR19160644-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160644-01Size:500 mg
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Description
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. (In Vitro) :Meropenem is intrinsically stable to dehydropeptidase-1 (DHP-1) degradation and Meropenem acts by inhibiting bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs) . Meropenem possesses broad-spectrum in vitro activity, which includes activity against many Gram-positive, Gram-negative and anaerobic bacteria; Meropenem lacks activity against Enterococcus faecium, methicillin-resistant Staphylococcus aureus and Stenotrophomonas maltophilia. (In Vivo) :Meropenem (60 mg/kg; intraperitoneal injection; once; SD rats) treatment significantly reduces the incidence of pancreatic infection.
CAS Number
96036-03-2
Product Name Alternative
ICI 194660 | Merrem I.V. | SM-7338
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Water: 8 mg/mL (20.86 mM) ; DMSO: 77 mg/mL (200.8 mM)
Smiles
O=C (C (N12) =C (S[C@@H]3CN[C@H] (C (N (C) C) =O) C3) [C@H] (C) [C@]2 ([H]) [C@@H] ([C@H] (O) C) C1=O) O
Molecular Formula
C17H25N3O5S
Molecular Weight
383.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(4R,5S,6S) -3- (((3S,5S) -5- (dimethylcarbamoyl) pyrrolidin-3-yl) thio) -6- ((R) -1-hydroxyethyl) -4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

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