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Metoprolol succinate

CAT: 0013-GTR19160610-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160610-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension.Hypertension Approved (In Vitro) :Metoprolol (0-1000 μg/mL; 24-72 h) shows cytotoxic effect on U937 and MOLT-4 cells dose and time dependently. (In Vivo) :Metoprolol (2.5 mg/kg/h; infusion; 11 weeks) reduces proinflammatory cytokines and atherosclerosis in ApoE / Mice.Metoprolol (15 mg/kg/q12h; i.g.; 5 days) shows anti-inflammation and anti-virus effects in murine model with coxsackievirus B3-induced viral myocarditis.Metoprolol (2.5 mg/kg; i.v.; 3 bolus injections) significantly decreased activated caspase-9 protein expression and inhibits myocardial apoptosis in coronary microembolization (CME) rats.
CAS Number
98418-47-4
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
CC (C) NCC (COC1=CC=C (C=C1) CCOC) O.CC (C) NCC (COC1=CC=C (C=C1) CCOC) O.C (CC (=O) O) C (=O) O
Molecular Formula
C34H56N2O10
Molecular Weight
652.8159
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Butanedioic acid, compd. with 1-[4- (2-methoxyethyl) phenoxy]-3-[ (1-methylethyl) amino]-2-propanol (1:2)

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