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IACS-010759

CAT: 0013-GTR19168528-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168528-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IACS-010759 is an orally active small molecule inhibitor targeting mitochondrial complex I (NADH:ubiquinone oxidoreductase) . It disrupts oxidative phosphorylation and is utilized in both in vitro and in vivo research to study cancer metabolism, particularly in models reliant on oxidative phosphorylation for growth.
CAS Number
1570496-34-2
Product Name Alternative
H460, Inhibitor, IACS 010759, IACS 10759, IACS010759, IACS-010759, IACS10759, IACS-10759, orally, oxidative, OXPHOS, mitochondrial, Mitochondrial Metabolism, MitochondrialMetabolism, inhibit, Apoptosis, AML, complex, complex I of oxidative phosphorylation, phosphorylation
Field of Research
Cell Biology, Metabolism Research
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (25 mg/ml)
Smiles
Cc1nc (nn1Cc1cccc (c1) N1CCC (CC1) S (C) (=O) =O) -c1nc (no1) -c1ccc (OC (F) (F) F) cc1
Molecular Formula
C25H25F3N6O4S
Molecular Weight
562.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5-[5-Methyl-1-[[3- (4-methylsulfonylpiperidin-1-yl) phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4- (trifluoromethoxyphenyl]-1,2,4-oxadiazole

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