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NP118809

CAT: 0013-GTR19167701-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19167701-02Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NP118809 (39-1B4) is a selective and potent blocker of N-type (Cav2.2) voltage-gated calcium channels, exhibiting an IC50 of 0.11 μM. This small molecule is a valuable research tool for investigating pain pathways and neurotransmitter release in both cellular and animal models of neurological disorders.
CAS Number
41332-24-5
Product Name Alternative
NP 118809, NP118809, NP-118809, inhibit, Inhibitor, 39-1B4, Ca channels, Calcium Channel, Ca2+ channels, CalciumChannel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.74% (May vary between batches)
Solubility
DMSO:4.61 mg/mL (10.01 mM)
Smiles
O=C (CC (c1ccccc1) c1ccccc1) N1CCN (CC1) C (c1ccccc1) c1ccccc1
Molecular Formula
C32H32N2O
Molecular Weight
460.61
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Z-160

Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy.

CAS Number41332-24-5
PubChem CID4988454
IUPAC Name1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one
Molecular FormulaC32H32N2O
Molecular Weight460.6
XLogP6.1
Topological Polar Surface Area23.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count7
Heavy Atom Count35
Formal Charge0
Complexity581
SMILES
C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)CC(C4=CC=CC=C4)C5=CC=CC=C5
InChI
InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30,32H,21-25H2
InChIKey
VCPMZDWBEWTGNW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Z-160
CAS: 41332-24-5
CID: 4988454
Formula: C32H32N2O
MW: 460.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight460.6
XLogP36.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count7
Exact Mass460.251463648
Monoisotopic Mass460.251463648
Topological Polar Surface Area23.6 Ų
Heavy Atom Count35
Formal Charge0
Complexity581
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
A3666-100NP118809
A15192-200NP118809 200mg
A15192-100NP118809 100mg
A15192-500NP118809 500mg
MBS131517NP118809 (39-1B4; NP 118809; NP-118809)

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